Designed to follow the natural rise and fall of hormone levels
Lifelike28™ is a physician-guided bioidentical hormone therapy program developed by Bare Compounding Pharmacy. Instead of the same dose every day, your dose follows a 28-day pattern of higher and lower days, set by your prescriber and measured in clicks with a TICKER® metered-dose dispenser.
Before menopause, hormone levels are not constant. In a typical cycle, estrogen climbs to a peak around mid-cycle, dips, then rises again in the second half while progesterone builds to its own peak, before both fall at the end of the cycle.
Traditional hormone therapy
The same dose every day of the month: a flat line.
Lifelike28™ rhythmic dosing
A daily dose that rises and falls on a set 28-day schedule, modeled on that natural cycle pattern.
Your prescriber decides whether this approach is right for you and which strength (Step) to start with, based on your symptoms, history and lab work.
Bioidentical hormones
Estradiol, estriol, progesterone and testosterone that are structurally identical to the hormones your body makes.
Compounded for you
Prepared at Bare Compounding Pharmacy after we receive a prescription for you.
Measured in clicks
Each cream is dispensed in a TICKER® metered-dose dispenser, so each dose is measured by counting clicks.
10 strengths per hormone
Steps 1–10 use the same click schedule, so your prescriber can raise or lower the strength without changing your routine.
The 28-day pattern
Each hormone has its own schedule. The chart shows each hormone's daily dose as a percentage of its highest day in the cycle.
Estrogens (Biest & E2)ProgesteroneTestosterone
Estrogens (Biest 80/20 or estradiol) build to a peak on Day 13, ease off, rise again on Days 20–22 and taper toward the end of the cycle. Progesterone stays low through Day 14, rises to its peak on Day 21 and tapers after Day 25. Testosterone is steady, with a lower dose on Days 7, 14, 21 and 28.
How to use your Lifelike28™ dosing sheet
Match your sheet to your label. Use the sheet for the same hormone and Step number that's printed on your prescription label.
Find today's cycle day. Day 1 is the first day you use your medication, not the first day of the calendar month. Count each day after that in order to find your row on the sheet.
Count your clicks. The CLICKS column shows how many clicks to dispense. Each click of the TICKER® dispenses 0.05 g of cream, so 20 clicks equals 1 gram. Estrogen and progesterone sheets show two numbers (AM, PM): apply the first in the morning and the second in the evening. Testosterone is applied once a day, in the morning.
Apply to clean, dry skin. Rub the cream into the inner arms or inner thighs, or wherever your prescriber directs.
Questions? If you miss a dose or aren't sure which day you're on, call us before you change anything. Don't double up.
Dosing sheets
Select the hormone and Step on your prescription label to open its sheet (PDF). Each sheet prints two copies per page: keep one near where you apply your cream.
Prescription receivedYour participating prescriber sends your Lifelike28™ prescription to Bare Compounding Pharmacy.
We contact youWe confirm we have your prescription, get any information we need and answer your questions.
Ingredients checkedEach ingredient is evaluated for quality and potency before it's used.
Compounded and checkedLicensed pharmacists and pharmacy technicians prepare your medication using standardized formulas, equipment and procedures. A pharmacist checks it at several key steps, using an FMEA (failure mode and effects analysis) approach to quality assurance.
ShippedOrders usually ship the next business day and arrive within about five business days. Overnight and 2-day shipping are available. Some medications require an adult signature.
Ready to startYour package includes your dosing sheet, directions and our contact information. A pharmacist is available for counseling.
For prescribers
Lifelike28™ gives your practice a standardized way to prescribe rhythmic bioidentical hormone therapy:
Standardized formulations. Every Step is made with the same ingredients, equipment and procedures, using ingredients from reputable U.S. pharmacy wholesalers, for batch-to-batch consistency.
A defined set of strengths. Ten Steps per hormone keep prescribing simple and limit the number of possible doses.
Accurate dosing at home. Each preparation is dispensed in a TICKER® metered-dose dispenser. Patients follow the dosing sheet and can adjust within the schedule as you direct.
Get found by patients. Participating practices can be listed on our Find a Prescriber page.
To prescribe Lifelike28™, specify the hormone, the Step and the Lifelike28™ schedule. All ten Steps of a hormone use the same click schedule, so you adjust the strength by changing the Step number. One click delivers 0.05 g of cream (20 clicks = 1 g). We'll dispense the cream with the matching dosing sheet. See How to Prescribe for e-prescribing, fax and portal options, or call the pharmacy to discuss a formulation.
Strength by Step (mg per gram)
Hormone
Step 1
Step 2
Step 3
Step 4
Step 5
Step 6
Step 7
Step 8
Step 9
Step 10
Fill
Applied
E3/E2 Biest 80/20
0.25
0.5
1
1.5
2
3
4
5
6
8
30 g
AM & PM
E2 Estradiol
0.25
0.5
1
1.5
2
3
4
5
6
8
30 g
AM & PM
P Progesterone
20
40
60
80
100
120
140
160
180
200
31 g or 37 g
AM & PM
Tw Testosterone
2
4
6
8
10
12
14
16
18
20
17 g
AM only
Total daily dose range across the cycle (mg/day)
Hormone
Step 1
Step 2
Step 3
Step 4
Step 5
Step 6
Step 7
Step 8
Step 9
Step 10
Biest 80/20
0.1–0.35
0.2–0.7
0.4–1.4
0.6–2.1
0.8–2.8
1.2–4.2
1.6–5.6
2–7
2.4–8.4
3.2–11.2
Estradiol
0.1–0.35
0.2–0.7
0.4–1.4
0.6–2.1
0.8–2.8
1.2–4.2
1.6–5.6
2–7
2.4–8.4
3.2–11.2
Progesterone
6–52
12–104
18–156
24–208
30–260
36–312
42–364
48–416
54–468
60–520
Testosterone
0.3–1
0.6–2
0.9–3
1.2–4
1.5–5
1.8–6
2.1–7
2.4–8
2.7–9
3–10
Ranges run from each sheet's lowest-dose day to its highest-dose day. Biest 80/20 is 80% estriol (E3) and 20% estradiol (E2), and follows the same schedule and strengths as estradiol.
Estradiol (E2): daily dose by Stepmg/day. Lightest line = Step 1, darkest = Step 10.Progesterone: daily dose by Stepmg/day. Lightest line = Step 1, darkest = Step 10.
Important information
Lifelike28™ preparations are compounded medications. Compounded medications are not FDA-approved, which means the FDA has not reviewed them for safety, effectiveness or quality.
Hormone therapy is not right for everyone. Talk to your prescriber about the benefits and risks for you, and follow the directions on your prescription label.
Topical hormones can transfer to other people and pets through skin contact. Wash your hands after applying, and let the cream dry before skin contact with others.
Testosterone is a federally controlled substance (Schedule III). Controlled-substance prescriptions follow DEA and California Board of Pharmacy requirements.
Ask your healthcare provider whether Lifelike28™ is right for you, or find a prescriber near Folsom who works with our pharmacy. Questions about your dosing sheet? Call us at (916) 983-4900, Monday–Friday, 10:00 AM–6:00 PM.
At Bare Compounding Pharmacy, caring for you is our top priority. We'd love to hear how we did. Share your experience with a Google Review or Like us on Facebook, we appreciate your feedback and we strive to always keep improving!
